Cisco Compute Hyperconverged C220 M7 Node Family Data Sheet

Data Sheet

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Updated:April 30, 2024

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Updated:April 30, 2024


Cisco® Compute Hyperconverged with Nutanix accelerates and simplifies the delivery of infrastructure and applications, at a global scale, through best-in-class cloud-operating models, industry-leading flexibility, and enhanced support and resiliency capabilities so you can power your hybrid multicloud future with the industry’s most complete hyperconverged solution.

Product overview

Cisco Compute Hyperconverged with Nutanix

Cisco and Nutanix have partnered to introduce the IT industry’s most complete hyperconverged solution by integrating and validating Cisco servers, storage, networking, and SaaS operations with the Nutanix hybrid multicloud platform. Cisco Compute Hyperconverged with Nutanix is built, managed, and supported holistically to deliver a more seamless experience, foster innovation, and accelerate customers’ hybrid-cloud journeys.

Cisco Compute Hyperconverged C220 M7 Node family

Cisco Compute Hyperconverged C220 M7 Node family delivers performance, flexibility, and resiliency in a small footprint. Physically, nodes are deployed into clusters, with a cluster consisting of one or more Cisco Compute Hyperconverged C220 M7 All-Flash/All-NVme servers.

These servers can be interconnected and managed in two different ways:

     UCS Managed mode: The nodes are connected to a pair of Cisco UCS® 6400 Series or a pair of Cisco UCS 6500 Series fabric interconnects and managed as a single system using UCS Manager. The minimum number of nodes in such a cluster is three. These clusters can support both general-purpose deployments and mission-critical high-performance environments.

     Intersight Standalone mode: The nodes are connected to a pair of Top-of-Rack (ToR) switches and servers are centrally managed using Cisco Intersight®. While a minimum of three nodes are required to deploy a standard Nutanix cluster, we also offer an option to deploy a single-node cluster and a two-node cluster for Edge and branch locations and situations that already have a high-performance network fabric installed. Refer to the Cisco spec sheets for further detail on the use of 1-node and 2-node Nutanix clusters.

Features and benefits

Cisco Compute Hyperconverged C220 M7 All-Flash/All-NVMe with Intel® Xeon® Scalable Processors are excellent for a wide range of enterprise workloads, including cloud computing, Virtual Desktop Infrastructure (VDI), databases, and server virtualization.

Table 1.           Summary of features and benefits of Cisco Compute Hyperconverged C220 M7 All-Flash Node/All-NVMe node




  High memory capacity
  Up to 4 TB memory (32 x 128 GB DDR5 DIMMs)

4th Generation Intel Xeon Scalable Processors

  10-nanometer (nm) processor technology
  Massive processing power with up to 60 cores per socket
  Larger L2 and L3 cache
  Increased I/O Bandwidth with PCIe 5.0
  High-speed DDR5 memory technology for up to 4800 MT/s
  Multiple built-in accelerators for new functional capabilities across AI, analytics, security, and storage
  Platform level power savings to deliver sustainability goals

Unified network fabric (Optional)

  Low-latency, up to 8 x 10/25/50 Gigabit Ethernet connections or up to 4 x 40/100 Gigabit Ethernet connections
  Wire-once deployment model, eliminating the need to install adapters and re-cable racks and switches when changing I/O configurations
  Fewer interface cards, cables, and upstream network ports to purchase, power, configure, and maintain

Cloud-based services and management

Cisco Intersight® simplifies infrastructure operations across on-premises data centers, edge sites, and public clouds

  Use a software-as-a-service platform that bridges applications with infrastructure
  Correlate visibility and management across bare-metal servers, hypervisors, and application components
  Transform operations with artificial intelligence to reach needed scale and velocity

Nutanix Cloud Platform (NCP) includes Nutanix Cloud Infrastructure (NCI), Nutanix Cloud Management (NCM), and desktop services:

  NCI unifies compute, storage, and network, hypervisors and containers, in public or enterprise clouds
  NCM offers customers simplicity and ease of use to build and grow their cloud deployments and realize rapid ROI, by providing intelligent operations, self- service and orchestration, visibility and governance
  Desktop services offer hybrid-cloud infrastructure capabilities for on-premises Virtual Desktop Infrastructure (VDI) and Desktop-as-a-Service (DaaS) use cases.


  All-flash or All-NVMe configurations

      Deliver high-capacity configurations for the Cisco Compute Hyperconverged platform capacity layer

  Nutanix Unified Storage provides software-defined, scale-out storage solutions for enterprise Network Attached Storage (NAS) and object workloads for unstructured data, block storage for structured data, and backup storage

Enterprise data protection

  Synchronous and near-synchronous replication with option to use runbook automation
  Multisite asynchronous replication for disaster recovery
  Deduplication and compression
  Disaster recovery in cloud with Nutanix cloud clusters


  Data-at-rest encryption using self-encrypting drives and enterprise key management integration
  Trusted Platform Module (TPM), a chip (microcontroller) that can securely store artifacts, including passwords, certificates, and encryption keys, which are used to authenticate the platform (node). Supports TPM 2.0
  Software based data-at-rest encryption and micro-segmentation


  Management software: Cisco Intersight, Nutanix Cloud Infrastructure (NCI), Nutanix Cloud Management (NCM), desktop services
  Storage software: AOS Storage, Nutanix Unified Storage (NUS) - for files, objects, and volumes use cases
  Hypervisor: Nutanix Acropolis Hypervisor (AHV) and VMware vSphere

Product specifications

Table 2.           Common specifications for Cisco Compute Hyperconverged C220 M7 All Flash Node


Common specifications across the Cisco Compute Hyperconverged C220 M7 node family


  1RU of rack space per node


  One or two 4 th Gen Intel Xeon Scalable Processors (Sapphire Rapids)

Chip set

  Intel C741 series


  32 DDR5 DIMM slots: 16, 32, 64 and 128 GB up to 4800 MT/s
  4 TB using 32 x 128-GB DDR5 DIMMs
  50% peak bandwidth increase over DDR4-3200, with on-die ECC; all densities are Registered DIMMs (RDIMMs)


  Specific drive options are available for Cisco Compute Hyperconverged C220 nodes:
  C220 All Flash Node: 1.9 TB, 3.8 TB, 7.6 TB or 15.3 TB SSD disks (up to 10 drives per node)
  C220 All NVMe Node: 1.9 TB, 3.8 TB, 7.6 TB or 15.3 TB NVMe drives (up to 10 drives per node)
  Dual M.2 SATA SSDs with HW RAID support


  3 PCIe 4.0 slots or up to 2 PCIe 5.0 slots plus 1 dedicated 12-Gbps RAID controller slot and 1 dedicated mLOM slot

Graphics Processing Units (GPUs)

  NVIDIA L4 GPU card (optional)


  Cisco UCS Virtual Interface Card 15428 or 15238 or 15427 or 15237 (modular LAN on Motherboard)
  Quad 10/25/50 G or Dual 40/100 G Ethernet VIC (Cisco UCS Virtual Interface Card 15425 or 15235) (optional)
  Intel E810 dual- or quad-port Network Interface Card (Intersight Standalone Mode)
  Up to 256 I/O devices programmable on demand for hypervisor and virtual machine support

Cisco Integrated Management Controller (IMC)

  Integrated Baseboard Management Controller (BMC)
  Intelligent Platform Management Interface (IPMI) 2.0 compliant for management and control
  One 10/100/1000 Ethernet out-of-band management interface
  Command-line interface (CLI) and web GUI management tool for automated, lights-out management
  Keyboard, Video, and Mouse (KVM) console

Advanced reliability, availability, and serviceability (RAS) features

  Robust reporting and analytics
  Hot-swappable, front-accessible drives
  Dual-redundant fans and hot-swappable, redundant power supplies for enterprise-class reliability and a convenient latching lid for easy access to internal server
  Tool-free CPU insertion, enabling processor upgrades and replacements with less risk of damage
  Tool-free access to all serviceable items, and color-coded indicators to guide users to hot-pluggable and serviceable items
  Non-disruptive rolling upgrades using Nutanix Life-Cycle Manager (LCM)

Front-panel connector

  1 KVM console connector per node
(supplies 2 USB connectors, 1 VGA connector, and 1 serial connector)

Front-panel locator LED

  Helps direct administrators to specific servers in large data-center environments

Additional rear connectors

  1 Gigabit Ethernet management port
  1 RS-232 serial port (RJ45 connector)
  1 Video Graphics Array (VGA) video port (DB15 connector)
  2 USB 3.0 ports

Power and cooling

  One or two hot-pluggable power supplies
  Second power supply provides 1+1 redundancy
  770W, 1200W, 1600W, or 2300W AC power supplies or 1050 DC power supply
  8 hot-swappable fans for front to rear cooling

Rail-kit options

  Cisco ball-bearing rail kit with optional reversible cable-management arm


  Management software: Nutanix Cloud Infrastructure, Nutanix Cloud Management, desktop services
  Storage software: AOS Storage, Nutanix Unified Storage (files, objects, and volumes)
  Hypervisor: Nutanix Acropolis Hypervisor (AHV) and VMware vSphere

Ordering information

For a complete list of part numbers, refer to the Cisco Compute Hyperconverged C220 M7 All Flash specification sheet.

Cisco Unified Computing Services

Cisco, Nutanix, and our industry-leading partners deliver services that accelerate your transition to Cisco Compute Hyperconverged systems. Professional services can help you create an agile infrastructure, accelerate time to value, reduce costs and risks, and maintain availability during deployment and migration. After you have deployed your system, our services can help you improve performance, availability, and resiliency as your business needs evolve.

Product sustainability

Information about Cisco’s Environmental, Social, and Governance (ESG) initiatives and performance is provided in Cisco’s Corporate Social Responsibility (CSR) and sustainability reporting.

Table 3.           Cisco environmental sustainability information

Sustainability topic



Information on product-material-content laws and regulations


Information on electronic waste laws and regulations, including our products, batteries, and packaging

WEEE Compliance

Information on product takeback and reuse program

Cisco Takeback and Reuse Program

Sustainability inquiries


Cisco makes the packaging data available for informational purposes only. It may not reflect the most current legal developments, and Cisco does not represent, warrant, or guarantee that it is complete, accurate, or up to date. This information is subject to change without notice.

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Document history

New or Revised Topic

Described In


Update to include All-NVMe offering

Table 2

April 2024

Update for Intersight Standalone Mode

Table 2

February 2024

Initial release

Table 2

December 2023




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